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Displaying 210 of 2850 articles.

Researchers discover a new mechanism in childhood kidney cancer

A problem in reader proteins that identify which gene is up for expression may cause normal cells to turn malignant during development.

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Study sheds new light on how epigenetic events might spur disease

Research that began with the analysis of two developmental syndromes ultimately helped scientists understand how diverse epigenetic mechanisms can combine to drive tissue overgrowth in cancer.

Study pinpoints rare genetic change that may boost risk of HPV-related illness

The human papilloma virus is usually kept in check by the immune system, but scientists identified a genetic variant that makes some infected children prone to developing warts in the throat.

C. David Allis elected to the National Academy of Medicine

Allis, whose pioneering research established that enzymes that modify histone proteins, which package DNA in the nucleus, regulate gene expression, has been elected to the National Academy of Medicine.

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Study gives clues to the origin of Huntington’s disease, and a new way to find drugs

Using a new technique to study brain development, scientists were able to trace the causes of Huntington's back to early developmental stages when the brain has only just begun to form.

Jeffrey M. Friedman to receive 2020 Breakthrough Prize in Life Sciences

Friedman's discovery of the hormone leptin has transformed our understanding of obesity.

From the tiny testes of flies, new insight into how genes arise

A common birthplace of new genes, the male testes are a hotspot for biological innovation. Within these organs, scientists have found a trove of virgin genetic sequences—and a better understanding of how evolution moves forward.

With tiny technological tweezers, researchers uncover new aspects of cell division

Cell division is critical to creating and sustaining life. It’s also incredibly difficult to study. Now, advanced technology is enabling researchers to take their understanding of this process to the next level.

Three-dimensional model illuminates key aspects of early development

Researchers have created a new 3D model of human embryonic tissue that promises to shed light on critical components of development—including processes that go awry during pregnancy complications.

New research raises prospect of better anti-obesity drugs

Scientists have found a group of brain cells that influence body mass in two ways, by controlling how much we eat as well as how much energy we burn. The findings could lead to new drugs to help people shed weight.