Event Detail (Archived)
Optical Electrophysiology for Dissecting Cortical Microcircuits
- This event already took place in February 2020
- A Level Physics Seminar Room, Room A30, Smith Hall Annex (CRC)
Event Details
- Type
- Center for Studies in Physics and Biology Seminars
- Speaker(s)
-
Adam Cohen, Ph.D., professor, Harvard University
- Open to
- Public
- Contact
- Melanie Lee
- Phone
- (212) 327-8636
- Sponsor
-
Melanie Lee
(212) 327-8636
leem@rockefeller.edu - Notes
- Combined optogenetic perturbation and voltage imaging enables high-resolution mapping of bioelectrical dynamics in intact tissues. I will describe application to Layer 1 of the mouse barrel cortex. We developed techniques to distinguish the separate contributions of excitatory and inhibitory synaptic inputs to membrane potential. Using these tools, we deciphered how the sensory-evoked responses emerged from local network dynamics.