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Event Detail (Archived)

Optical Electrophysiology for Dissecting Cortical Microcircuits

  • February 18, 2020
  • 4:00 PM - 5:00 PM
  • A Level Physics Seminar Room, Room A30, Smith Hall Annex (CRC)

Event Details

Type
Center for Studies in Physics and Biology Seminars
Speakers
Adam Cohen, Ph.D., professor, Harvard University

Sponsor
Melanie Lee
(212) 327-8636
leem@rockefeller.edu
Open to
Public
Contact
Melanie Lee
Phone
(212) 327-8636
Notes
Combined optogenetic perturbation and voltage imaging enables high-resolution mapping of bioelectrical dynamics in intact tissues. I will describe application to Layer 1 of the mouse barrel cortex. We developed techniques to distinguish the separate contributions of excitatory and inhibitory synaptic inputs to membrane potential. Using these tools, we deciphered how the sensory-evoked responses emerged from local network dynamics.


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