- Friday Lecture Series
Vamsi Mootha, M.D., professor of systems biology and of medicine, Harvard Medical School and Massachusetts General Hospital, institute member, Broad Institute of MIT and Harvard; investigator, Howard Hughes Medical Institute
Mitochondrial dysfunction accompanies a spectrum of conditions—ranging from rare, inborn errors of metabolism to the aging process itself. Mitochondria contain their own genome (mtDNA) that encodes 13 proteins, while all remaining 1000+ proteins are encoded in the nuclear genome and imported into the organelle. These two genomes must be coordinated in space and time to ensure metabolic homeostasis. In this talk Dr. Mootha will present his lab’s efforts aimed to systematically (1) define the molecular genetic basis of mitochondrial disease, (2) understand its biochemical pathogenesis, and (3) discover new therapeutic strategies.
Dr. Mootha is an investigator of the Howard Hughes Medical Institute and directs a research laboratory based at Massachusetts General Hospital. He is also Professor of Systems Biology and Medicine at Harvard Medical School and an institute member of the Broad Institute of MIT and Harvard, where he is co-director of the metabolism program.
Dr. Mootha received his undergraduate degree in Mathematical and Computational Science at Stanford University and his M.D. from Harvard Medical School in the Harvard-MIT Division of Health Sciences and Technology. After completing his internship and residency in internal medicine at Brigham and Women's Hospital, he pursued postdoctoral training both at the Whitehead Institute. Dr. Mootha has received a number awards, including a Macarthur “Genius Grant,” a Padma Shri from the government of India, and the King Faisal International Prize for Science. He is a member of the National Academy of Sciences.
- Open to
- Richard Lifton, Ph.D.
- Refreshments, 3:15 p.m. - 3:45 p.m., Abby Lounge
- Justin Sloboda
- (212) 327-7785