Allis is recognized for his foundational research on the unexpected regulation of gene activation by modifications to proteins that package DNA, work with implications for many diseases including cancer. The Breakthrough Prize is worth $3 million, making it the richest prize in the life sciences, roughly double the Nobel Prize.
Titia Lange is recognized for her discovery of the mechanisms by which mammalian telomeres are protected from deleterious DNA repair and damage responses. The Gairdner is Canada’s highest scientific award and is considered among the most prestigious international prizes in science.
Allis’s discovery that chemical “tags” bind to specific sections of histone proteins in order to activate or silence nearby genes has ignited the field of epigenetics, a relatively new area of study which explores the inheritance of physical changes that cannot be traced back to mutations in the DNA sequence. The Japan Prize, worth approximately half a million dollars, is among the most prestigious prizes in science.
Casanova is honored for his work on host genes and their products in infectious diseases. His lab is interested in why some children develop severe infectious diseases after coming into contact with certain pathogens, while most other children do not.
Darnell, who focuses on understanding a group of rare brain diseases, the paraneoplastic neurologic disorders (PNDs), and how they arise in conjunction with immune responses to cancer, is one of 84 newly elected members announced today by the Academy.
Casanova is recognized for discovering “holes” in the immune systems of otherwise healthy children that make them susceptible to specific, sometimes life-threatening infectious diseases.
The Rockefeller University Distinguished Teaching Award
Daniel Mucida, Ph.D.
The Rockefeller University Distinguished Teaching Award
Agata Smogorzewska, M.D., Ph.D.
Charles-Leopold Mayer Prize, French Academy of Sciences
C. David Allis, Ph.D.
Paradigm Award, Breakthrough Institute
Jesse H. Ausubel
American Association for Cancer Research Academy Fellow
Günter Blobel, M.D., Ph.D.
Presidential Award, Clinical Immunology Society
Jean-Laurent Casanova, M.D., Ph.D.
Norman J. Siegel New Member Outstanding Science Award, American Pediatric Society
Jean-Laurent Casanova, M.D., Ph.D.
Research Award, Jain Foundation
Brian T. Chait, D.Phil.
American Association for Cancer Research Academy Fellow
James E. Darnell, Jr., M.D.
American Association for Cancer Research Academy Fellow
Titia de Lange, Ph.D.
American Association for the Advancement of Science fellowship
Jeffrey M. Friedman, M.D., Ph.D.
Pezcoller Foundation International Award for Cancer Research
Elaine Fuchs, Ph.D.
Prince Mahidol Award, Kingdom of Thailand
David Ho, M.D.
L’Oreal-UNESCO Award in Life Science
Kayo Inaba, Ph.D.
Alfred P. Sloan Foundation Research Fellowship
Career Development Award, Human Frontier Science Program
Sebastian Klinge, Ph.D.
Lifetime Science Award, National Institute on Drug Abuse
Mary Jeanne Kreek, M.D.
40 Under 40, Cell
Luciano Marraffini, Ph.D.
The Practitioners Society of New York membership
Michel C. Nussenzweig, M.D., Ph.D.
Research Award, Jain Foundation
Michael P. Rout, Ph.D.
Invitation Fellowship Program for Research in Japan
Thomas P. Sakmar, M.D.
Regeneron Prize for Creative Innovation, Regeneron Pharmaceuticals, Inc.
Daniel Schramek, Ph.D.
Doris Duke Charitable Foundation Clinical Research Mentorship
Agata Smogorzewska, M.D., Ph.D.
Pershing Square Sohn Prize for Young Investigators in Cancer Research
Agata Smogorzewska, M.D., Ph.D.
Burke Award, Burke Rehabilitation Hospital
Marc Tessier-Lavigne, Ph.D.
NY/NJ CEO Lifetime Achievement Award
Marc Tessier-Lavigne, Ph.D.
European Inventor Award, European Patent Office
Thomas Tuschl, Ph.D.
American Association for the Advancement of Science fellowship
Leslie B. Vosshall, PD.