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Stem Cell Research at the Rockefeller University


What causes a stem cell to become a neuronal cell? Rockefeller scientists have identified a list of genes involved in human embryonic stem cell differentiation, the process (pictured above) by which an embryonic stem cell becomes any one of dozens of types of cells in the body.
 

In the scientific community and general public, a great deal of excitement exists about the potential of using stem cells to repair diseased or damaged organs. Rockefeller University scientists are conducting basic research to improve scientific understanding of the biology of stem cells. Such basic research is crucial for the development of new treatments for diabetes, cancer, heart disease, stroke, spinal cord injury and such neurodegenerative disorders as Parkinson's and Alzheimer's diseases.


Researchers

Ali H. Brivanlou
Basic understanding of human development, tissue transplant, regenerative medicine

Many members of the scientific community regard Ali Brivanlou as a leader in the study of embryonic stem (ES) cells. His current studies build upon a decade of basic research with laboratory mice and frogs that has advanced our understanding about the embryonic development of the brain and other components of the nervous system and the formation of other organs. More...


Elaine Fuchs
Cancer, skin disorders

Elaine Fuchs studies the cell biology, genetics and development of skin and hair. Her basic research on the molecular mechanics underlying development and differentiation of these tissues addresses one of the fundamental questions of stem cell biology: How do stem cells "know" their fate? More...


Peter Mombaerts
Neurodegenerative diseases, tissue transplant

Peter Mombaerts is a specialist in genetic manipulation of the mouse, the most prominent experimental mammal in modern biology. He focuses most of his efforts toward understanding the origin and development of the cells of the brain that enable the sense of smell. More...


Anura Rambukkana
Regenerative medicine, peripheral nerve disease

Anura Rambukkana is investigating the possibility of reprogramming adult cells to make them more like ES cells, based on his discoveries about bacteria-induced reprogramming. More...


Thomas P. Sakmar
Vision disorders

Thomas Sakmar studies signal transduction, the process by which signals from outside a cell are relayed across the cell's membrane and into its interior, where they can elicit a response. Much of his work has focused on molecules in the retina, with implications for understanding a variety of serious vision disorders such as macular degeneration and retinitis pigmentosa. More...


Markus Stoffel
Type 1 diabetes

Markus Stoffel is a physician-scientist who aims to develop therapeutic transplants to replace damaged insulin-producing cells with healthy ones grown from lab cultures of stem cells. More...


Last Modified: 03/15/05 09:44

NEWS RELEASES

May 23, 2005
Stem cell research in New York City receives pivotal boost from The Starr Foundation

Sept. 2, 2004
Single isolated mouse skin cell generates variety of epidermal tissues

August 03, 2004
Rockefeller University establishes stem cell research center

March 26, 2004
Mouse produced by cloning from a single neuron

January 5, 2004
Feeder-free system pioneered at Rockefeller University

December 11, 2003
New method of identifying and isolating stem cells

August 14, 2003
Building hair from the ground up

July 3, 2003
Genetic clues to stem cells' unlimited potential

March 21, 2003
Proteins push cells to produce hair instead of skin

May 1, 2001
Embryonic stem cell lines from adult mice



LINKS

National Institutes of Health

Harvard University

University of Wisconsin-Madison

Stanford University

Cambridge University

President's Council on Bioethics

International Society for Stem Cell Research

Juvenile Diabetes Research Foundation


CONTACT

To interview Rockefeller University scientists contact ...

Joseph Bonner
Director of Communications
(212) 327-8998
bonnerj@rockefeller.edu


Kristine A. Kelly
Science Writer / Media Relations
(212) 327-7146
kkelly@rockefeller.edu