Stem Cell Derivation Core

Stem Cell Derivation Core derives human embryonic stem cell (hESC) lines from normal as well as diseased embryos. The unit isolates, characterizes and maintains new hESC lines. It uses classical methods and also works to develop new derivation methods that bypass the requirements of feeder influence and improve the maintenance conditions of hESC pluripotency. The facility works to futher improve the ability of the newly derived lines to generate embryoid bodies and teratomas for germ layer specification assays and to develop new in vivo and in vitro assays to test the totipotency of individual lines.

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