Dr. Yufeng Wei received his Ph.D. in Chemistry from Columbia University in the City of New York, and did his postdoc at the University of Michigan. He is also an assistant professor in the Department of Chemistry and Biochemistry at Seton Hall University. His lab is focusing on structural biology of proteins and nucleic acids using NMR spectroscopy. He is also working on developing and implementing new NMR technologies on structural determination of biomolecules. He has extensive experience and knowledge in both solution and solid-state NMR spectroscopy.
Selected Publications:
Yufeng Wei, Shaohua Liu, Jörn Lausen, Christopher Woodrell, Seongeun Cho, Nikolaos Biris, Naohiro Kobayashi, Yu Wei, Shigeyuki Yokoyama, and Milton H. Werner, "A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription", Nat. Struct. Mol. Biol. 2007, 14, 653-661.
Yufeng Wei and Milton H. Werner, "iDC: A Comprehensive Toolkit for the Analysis of Residual Dipolar Couplings for Macromolecular Structure Determination", J. Biomol. NMR 2006, 35, 17-25.
Paul E. Carrington, Cristinel Sandu, Yufeng Wei, Justine M. Hill, Gaku Morisawa, Ted Huang, Evridipis Gavathiotis, Yu Wei, and Milton H. Werner, "The Structural of FADD and Its Mode of Interaction with Procaspase-8", Mol. Cell 2006, 22, 599-610.
Lester J. Lambert, Yufeng Wei, Virgil Schirf, Borries Demeler, and Milton H. Werner, "T4 AsiA blocks DNA recognition by remodeling 70 region 4", EMBO J. 2004, 23, 2952-2962.
A. Ramamoorthy, Yufeng Wei, and Dong-Kuk Lee, "PISEMA Solid-State NMR Spectroscopy", Annu. Rep. NMR Spectrosc. 2004, 52, 1-52.
Justin H. Hill, Gaku Morisawa, Tad Kim, Ted Huang, Yu Wei, Yufeng Wei, and Milton H. Werner, "Identification of an Expanded Binding Surface on the FADD Death Domain Responsible for Interaction with CD95/Fas", J. Biol. Chem. 2004, 279, 1474-1481.
Yufeng Wei, Dong-Kuk Lee, Ann E. McDermott, and A. Ramamoorthy, "Recovery of Dipolar and Chemical Shift Anisotropic Interactions and Sideband Enhancement under Magic Angle Spinning", J. Magn. Reson. 2002, 158, 23-35.
Yufeng Wei, Dong-Kuk Lee, K. J. Hallock, and A. Ramamoorthy, "One-Dimensional 1H-Detected Solid-State NMR Experiment to Determine Amide-1H Chemical Shifts in Peptides", Chem. Phys. Lett. 2002, 351, 42-46.
Yufeng Wei and A. Ramamoorthy, "Two-Dimensional 15N-15N Isotropic Chemical Shift Correlation Established by 1H Spin Diffusion in Biological Solids", Chem. Phys. Lett. 2001, 342, 312-316.
Yufeng Wei, Dong-Kuk Lee, and A. Ramamoorthy, "Solid-State 13C NMR Chemical Shift Anisotropy Tensors of Polypeptides", J. Am. Chem. Soc. 2001, 123, 6118-6126.
Dong-Kuk Lee, Yufeng Wei, and A. Ramamoorthy, "A Two-Dimensional Magic Angle Decoupling and Magic Angle Turning Solid-State NMR Method - An Application to Study Chemical Shift Tensors from Peptides That Are Non-Selectively Labeled with 15N Isotope", J. Phys. Chem. B 2001, 105, 4752-4762.
Yufeng Wei, Dong-Kuk Lee, and A. Ramamoorthy, "One-Dimensional Dipolar-Shift Spectroscopy Under Magic Angle Spinning to Determine the Chemical-Shift Anisotropy Tensors", Chem. Phys. Lett. 2000, 324, 20-24.
Yufeng Wei, Angel C. deDios, Ann E. McDermott, "Solid State 15N Chemical Shift Anisotropy of Histidine: Experimental and Theoretical Studies of Hydrogen Bonding", J. Am. Chem. Soc. 1999, 121, 10389-10394.
Yufeng Wei, Ann E. McDermott, "Effects of Hydrogen Bonding on 1H Chemical Shifts", in Modeling Chemical Shifts: Gaining Insights into Structure and Environment, ACS Symposium Series, 1999, American Chemical Society: Washington, D.C., pp. 177-193.