The university maintains facilities for both nuclear magnetic resonance spectroscopy and optical spectroscopy. The Spectroscopy Center provides access to optical spectroscopic equipment for use in studies of the structure, function and dynamics of biological macromolecules. The center has different types of spectroscopic instrumentation: stopped-flow fluorescence, Fourier transform infrared (FTIR), circular dichroism (CD) and surface plasmon resonance (SPR). Educational efforts are devoted both to training frequent users and providing general background in applications of spectroscopy to structural biology and chemistry. Occasional users of the facilities may have spectra produced for them. More frequent users are encouraged and trained to operate the instruments themselves.

The center also provides access to nuclear magnetic resonance spectrometers (one 400 mHz and one 600 mHz equipped with a cryoprobe) for use in studies of the structure, function and dynamics of macromolecules, as well as spectroscopic fingerprint of peptides and small organic molecules. The center offers extensive training in basic and advanced NMR experiments and also provides access to high field spectrometers at the New York Structural Biology Center.