Agenda


Tuesday, September 12

6:00 p.m. Welcome
Torsten Wiesel, President, The Rockefeller University

Keynote Lecture (Open to the public)
Coalescence of the Biological Sciences
Arthur Kornberg, Stanford University, USA

Please note: Registration is required to attend the following programs.

Wednesday, September 13

Molecular Recognition and Response

Chair: John Kuriyan, The Rockefeller University/Howard Hughes Medical Institute

9:00 a.m. The Architecture of Protein/DNA Complexes in Transcriptional Regulation
Stephen C. Harrison
Harvard University/Howard Hughes Medical Institute, USA

9:55 a.m. Regulation by Phosphorylation
Louise N. Johnson, University of Oxford, U.K.

11:10 a.m. The Role of NMR in Structural Biology
Kurt Wüthrich, ETH, Switzerland

12:05 p.m. Chirality and Macromolecular Recognition
Peter S. Kim, Massachusetts Institute of Technology/Howard Hughes Medical Institute, USA

Design of Biomolecules

Chair: Henri Buc, Institut Pasteur, France

2:30 p.m. Pyranosyl-RNA
Albert Eschenmoser, ETH, Switzerland

3:25 p.m. Supramolecular Chirality and Self-Assembly
Jean-Marie Lehn, Université Louis Pasteur, France

4:20 p.m. Chemical Approach to Understanding and Controlling Signal Transduction
Stuart Schreiber, Harvard University/Howard Hughes Medical Institute, USA

Thursday, September 14

Macromolecular Assemblies

Chair: Stephen K. Burley, The Rockefeller University/Howard Hughes Medical Institute

9:00 a.m. Functional Organization of the Nicotinic Receptor: A Membrane Allosteric Protein
Jean-Pierre Changeux, Institut Pasteur, France

9:55 a.m. Bacteriorhodopsin Structure and Structural Changes during Proton Pumping
Richard Henderson, MRC Cambridge, U.K.

11:10 a.m. Curing the Common Cold
Michael G. Rossmann, Purdue University, USA

12:05 p.m. Some Structural Biology of Cellular Immunity
Don C. Wiley, Harvard University, USA

RNA Biology

Chair: Dinshaw Patel, Sloan-Kettering Institute, USA

2:00 p.m. RNA as an Enzyme: Chemistry and Structure
Thomas R. Cech, University of Colorado/Howard Hughes Medical Institute, USA

3:25 p.m. Directed Molecular Evolution of Catalytic RNA and DNA
Gerald F. Joyce, Scripps Research Institute, USA

4:20 p.m. The Cell Nucleolus: Yet Another RNA Machine
Joan Steitz, Yale University/Howard Hughes Medical Institute, USA

Friday, September 15

A Chiral World

Chair: William Agosta, The Rockefeller University

9:00 a.m. Enzyme Catalyzed Racemization: Le Monde Achirale
Gregory A. Petsko, Brandeis University, USA

9:55 a.m. Chiral Metal Complexes and DNA: Recognition and Reaction
Jacqueline K. Barton, California Institute of Technology, USA

11:10 a.m. Molecular Recognition with Small Molecules
Julius Rebek, Jr., Massachusetts Institute of Technology, USA

12:05 p.m. Protein Structure with an Expanded Genetic Code
Peter G. Schultz, University of California, Berkeley/Howard Hughes Medical Institute, USA

1:00 p.m. Closing Remarks
Stephen K. Burley, The Rockefeller University/Howard Hughes Medical Institute


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