HOME   RESEARCH   PEOPLE   PUBLICATIONS CRYSTAL GALLERY  CONTACT  Using x-ray vision, he keeps his eye on the bacteria "Dr. C. Erec Stebbins, head of Rockefeller University's Laboratory of Structural Microbiology, spends much of his time using a nearly 100-year-old investigative tool..." -The New York Times Threading a narrow needle "A high-resolution crystal structure obtained by Jorge E. Galán, a microbiologist at Yale..." -Chemical & Engineering News Rockefeller researchers solve structure for deadly bacterial toxin "Researchers at Rockefeller University, New York, have determined the structure of a potent DNA-damaging protein..." -Drug Discovery & Development A salmonella invasion protein that acts as a "molecular staple" "Salmonella invasion protein A (SipA) is an important virulence factor injected into host cells, where it modulates the cytoskeleton by polym-erizing actin..." -Science Independent Faculty Publications 1: M. Lilic, V. E. Galkin, A. Orlova, M. S. VanLoock, E. H. Egelman, and C. E. Stebbins. (2003). "Salmonella SipA Polymerizes Actin by Stapling Filaments with non-Globular Protein Arms". Science, 301,1918-1921 [Abstract]  [pdf] 2: D. Nesic, Y. Hsu, and C.E. Stebbins. (2004). "Assembly and function of a bacterial genotoxin." Nature, 429, 429-433 [Abstract]  [pdf] 3: X. Hu, M. Vujanac , and C.E. Stebbins. (2004). "Computational Analysis of Tyrosine Phosphatase Inhibitor Selectivity for the Virulence Factors YopH and SptP." J Mol Graph Model, 23,175-87 [Abstract]  [pdf] 4: X. Hu and C.E. Stebbins. (2005). "Molecular docking and 3D-QSAR studies of Yersinia protein tyrosine phosphatase YopH inhibitors." Bioorg Med Chem. 13, 1101-9. [Abstract]  [pdf] 5: D. Nesic and C.E. Stebbins. (2005). "Mechanisms of Assembly and Cellular Interactions for the Bacterial Genotoxin CDT." PLoS Pathogens, Nov 18;1(3):e28. [Abstract]  [pdf] 6: R. Janjusevic, R.B. Abramovitch, G.B. Martin, and C.E. Stebbins. (2006). "A Bacterial Inhibitor of Host Programmed Cell Death Defenses is an E3 Ubiquitin Ligase." Science, 311, 222-6. [Epub 2005 Dec 22]. [Abstract]  [pdf] 7: X. Hu, D. Nesic, and C.E. Stebbins. (2006). "Comparative Structure-Function Analysis of Cytolethal Distending Toxins." PROTEINS, Feb 1;62(2):421-34. [Abstract]  [pdf] 8: M. Lilic, M. Vujanac, and C.E. Stebbins. (2006). "A Common Structural Motif in the binding of Virulence Factors to Bacterial Secretion Chaperones." Mol. Cell. 21(5):653-64. [Abstract]  [pdf] 9: A.B. Abramovitch, R. Janjusevic, C.E. Stebbins, and G.B. Martin. (2006). "Type III effector AvrPtoB requires intrinsic E3 ubiquitin ligase activity to suppress plant cell death and immunity". Proc Natl Acad Sci U S A. 103(8):2851-6. [Abstract]  [pdf] 10: X. Hu and C.E. Stebbins. (2006). "Dynamics of the WPD Loop of the Yersinia Protein Tyrosine Phosphatase." Biophys J. 91(3):948-56. [Abstract]  [pdf] 11: S. Mariana Margarit, Walter Davidson, Lee Frego, and C.E Stebbins. (2006). "A Steric Antagonism of Actin Polymerization by a Salmonella Virulence Protein." Structure, Aug;14(8):1219-29. [Abstract]  [pdf] 12: G. Prehna, M. I. Ivanov, J.B. Bliska, and C.E. Stebbins. (2006). "Yersinia Virulence Depends on Mimicry of Host Rho-family Nucleotide Dissociation Inhibitors." Cell, 126(5): 869-80. [Abstract]  [pdf] 13: X. Hu and C.E. Stebbins. (2006). "Dynamics and Assembly of the Cytolethal Distending Toxin." PROTEINS, 2006 Oct 10; [Epub ahead of print]. [Abstract]