Brain Cell Migration Movies from the Hatten Lab at Rockefeller University
Cell Migration
Hatten and Edmondson, 1987. (J. Neurosci.)
Migration of cerebellar granule cells along astroglial fibers in vitro. Immature granule neurons, purified
from early postnatal cerebellum, extend a specialized, migratory process along the underlying glial fiber. In this sequence,
a neuron moves along a glial fiber at approximately 50 microns/h. As
the neuron moves, lamellipodia and filopodia extend and retract along the length of the migratory process, enwrapping
the glial guide. The neuron forms an interstitial junction along the length of the cell soma, which is released
as the cell begins to move.
Cell Migration Movies Contents Page
