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| David Gadsby, Rockefeller University | |
| Jack Kaplan, University of Illinois at Chicago | |
| Jerry Lingrel, University of Cincinnati Medical School |
Wednesday, September 7
Symposium Session I: Atomic structure of cation pumps
| Paul De Weer, Chair (University of Pennsylvania Medical School, USA | Introductory remarks |
| Yuji Sugita (University of Tokyo, Japan) | SR Ca-ATPase atomic structure and molecular dynamics simulations |
| Jesper Møller (University of Aarhus, Denmark) | Structure and mechanism of SR Ca-ATPase |
| Steven Karlish (Weizmann Institute, Israel) | Towards Na,K-ATPase structure |
Symposium Session II: Cation binding sites
| Jean-Daniel Horisberger, Chair (University of Lausanne, Switzerland) | Introductory remarks |
| Peter Jørgensen (University of Copenhagen, Denmark) | Binding sites for Mg-ATP, and Na and K ions, in Na,K-ATPase |
| JoséArgüello (Worcester Polytechnic Institute, USA) | Heavy metal binding sites in P-IB-type ATPases |
| Hans-Jürgen Apell (University of Konstanz, Germany) | Binding sites and ion transport in P-type ATPases |
| Pablo Artigas (Rockefeller University, USA) | Na,K-ATPase ion translocation pathway |
Symposium Session III: Ion transport mechanisms
| Luis Beaugé, Chair (Institute M y M Ferreira, Argentina) | Introductory remarks |
| Giuseppe Inesi (University of Maryland School of Medicine, USA) | Substrate, product, and gating in SR Ca-ATPase |
| Jens Peter Andersen (University of Aarhus, Denmark) | Rapid kinetics, phosphoenzyme, and SR Ca-ATPase mechanism |
Symposium Session IV: Cation pump subunit interactions
| Kazuya Taniguchi, Chair (Hokkaido University, Japan) | Introductory remarks |
| Ernst Bamberg (MPI Biophysics, Frankfurt, Germany) | Subunit conformational dynamics of P-type ATPases |
| Jack Kaplan (University of Illinois at Chicago, USA) | Subunit interactions and trafficking |
| Ayyappan Rajasekaran (University of California Los Angeles, USA) | Na,K-ATPase in epithelial cell polarization |
Thursday, September 8
Symposium Session V: Inherited dysfunction of cation pumps
| Carolyn Slayman, Chair (Yale University School of Medicine) | Introductory remarks |
| Kathy Sweadner (Massachusetts General Hospital, USA) | Na,K-ATPase alpha subunit mutations in neurological disease |
| Rhoda Blostein (McGill University, Canada) | Functional effects of Na,K-ATPase disease-associated mutations |
| Amy Moseley (University of Cincinnati Medical School, USA) | Behavioral abnormalities in Na,K-ATPase haploinsufficient mice |
| Svetlana Lutsenko (Oregon Health and Science University, USA) | Human Cu-ATPases in Menkes and Wilson diseases |
Symposium Session VI: Late-breaking science
| Speakers to be determined |
Friday, September 9
Symposium Session VII: Regulation of cation pumps
FXYD proteins
| Michael Caplan, Chair (Yale University School of Medicine, USA) | Introductory remarks |
| Kathi Geering (University of Lausanne, Switzerland) | Na,K-ATPase regulation by FXYD proteins |
| Flemming Cornelius (University of Aarhus, Denmark) | FXYD/alpha interactions in Na,K-ATPase regulation |
| Haim Garty (Weizmann Institute, Israel) | Na,K-ATPase regulation by FXYD proteins |
Phospholamban and sarcolipin
| Don Bers, Chair (Loyola University, USA) | Introductory remarks |
| David MacLennan (University of Toronto, Canada) | SR Ca-ATPase regulation by phospholamban and sarcolipin |
| David Thomas (University of Minnesota, USA) | Molecular dynamics of SR Ca-ATPase regulation by phospholamban |
Specific P-type ATPase inhibitors
| Robert Farley, Chair (University of Southern California, USA) | Introductory remarks |
| Jan Joep De Pont (Nijmegen Center for Molecular Life Sciences, Holland) | Ouabain binding sites in Na,K-ATPase |
| George Sachs (University of California Los Angeles, USA) | Inhibitor binding sites in H,K-ATPase |
Receptor-mediated regulation
| Carlos Pedemonte, Chair (University of Houston, USA) | Introductory remarks |
| Alejandro Bertorello (Karolinska Institute, Sweden) | GPCR signals and intracellular traffic of Na,K-ATPase |
Saturday, September 10
Symposium Session VIII: Physiological roles of cation pumps
| Mordecai Blaustein, Chair (University of Maryland, USA) | Introductory remarks |
| Jerry Lingrel (University of Cincinnati Medical School, USA) | Gene targeting of Na,K-ATPase alpha isoforms |
| Gary Shull (University of Cincinnati Medical School, USA) | Gene targeting of Ca-transporting ATPases |
| J. Iasha Sznajder (University of Chicago, USA) | Na,K-ATPase in lung edema clearance |
There will be two formal poster-presentation sessions, one on Thursday afternoon and the other on Friday
afternoon. But posters will be available for viewing and informal discussion during the entire meeting, those of the
first session throughout Wednesday and Thursday, and those of the second session throughout Friday and Saturday.
The organizers expect to make adjustments to the scientific program, including selection of topics and speakers for
the late-breaking science session, after the receipt of abstracts in April.
| Go back | Updated: February 7, 2005 |