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Barry S. Coller
David Rockefeller Professor and Physician-in-Chief

My laboratory is devoted primarily to investigating platelet physiology, vascular biology and adhesion phenomena in sickle cell disease. We had produced monoclonal antibodies that can inhibit platelet aggregation and the adhesion of sickle red blood cells to the blood vessel wall in an animal model system. One of these antibodies has been developed into a drug (abcixinab) to prevent ischemic complications of percutaneous coronary infarctions and unstable angina. Among the ongoing projects are:

Publications
Publications