Laboratory of Mass Spectrometry and Gaseous Ion Chemistry
Brian T. Chait
Overview
Research
Lab Members
Publications
Tools
Protocols
Tutorials
Contact Us

The Rockefeller University
The Rockefeller University
1230 York Avenue,
New York, NY 10065
(212) 327-8000


National Center of Research Resources
National Resource
for the Mass Spectrometric
Analysis of Biological
Macromolecules

TOOLS

ProFound
ProFound is a tool for searching a protein sequence collections with peptide mass maps. A Bayesian algorithm is used to rank the protein sequences in the database according to their probability of producing the peptide map.

ProteinInfo
ProteinInfo is a collection of tools for retrieval and analysis of protein sequences. The capabilities of the analysis tools include peptide mapping, mass spectrometric fragmentation analysis, disulfide mapping, etc.

PeptideMap
PeptideMap is a tool for finding modifications on polypeptide sequences. The modifications can be affecting single amino acids (e.g. phoshorylation or oxidation) or cross-linking two amino acids (e.g. disulfide bonds or chemical cross-linking reagents).

PepFrag
PepFrag is a tool for identifying proteins from a collection of sequences that matches a single tandem mass spectrum.

X! Tandem
X! Tandem is a tool for identifying proteins from a collection of peptide sequences that matches tandem mass spectra.

X! Hunter
X! Hunter is a tool for identifying proteins that matches tandem mass spectra to a library of spectra that have been confidently assigned to a particular peptide sequence.

GPMDB
GPMDB is a database of tandem mass spectra and their assigned peptide sequences. It is designed to aid in the difficult process of validating peptide MS/MS spectra.

NCDIR Strain Database
The National Center for Dynamic Interactome Research (NCDIR) Strain Database