OVERVIEW

We develop proteomic tools for dissecting cellular function, with a special emphasis on the mass spectrometry (MS) of peptides and proteins. And we apply these tools to the study of challenging biological problems.

Research Projects

• Novel tandem MS instrumentation for ultrasensitive, rapid & comprehensive characterization of proteins
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• Methods for studying dynamic protein interactions
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• Method for elucidating the domain structures of proteins
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• Comprehensive Analysis of Viral Host Interactions
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• Comprehensive Description of Specific Chromosomal Regions
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• Cell Specific Dissection of the Macromolecular Components of Synapses in the Mammalian Brain: Unraveling the Molecular Synaptic Code