Publications
- Talekar A, Pessi A, Glickman F, Sengupta U, Briese T, et al. (2012) Rapid Screening for Entry Inhibitors of Highly Pathogenic Viruses under Low-Level Biocontainment. PLoS ONE 7(3): e30538. doi:10.1371/journal.pone.0030538
- Pipalia, N.H., Cosner, C.C., Huang, A, Chatterjee, A., Bourbon, P., Farley, N., Helquist, P., Wiest, O., and Maxfield, F.R. (2011) Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick Type C1 mutant human fibroblasts. Proc. Natl. Acad. Sci., USA, 108: 5620-5625.
- Rujoi, M., Pipalia, N.H., and Maxfield, F.R. (2010) Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells. PLoSONE 5: e12788. doi:10.1371/journal.pone.0012788.
- Ahn HJ, Zamolodchikov D, Cortes-Canteli M, Norris EH, Glickman JF, Strickland S. Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21812-7. Epub 2010 Nov 22. PubMed PMID: 21098282; PubMed Central PMCID: PMC3003082.
- VanderVen, B.C., Hermetter, A., Huang, A., Maxfield, F.R., Russell, D.G., and Yates, R.M. (2010), Development of a novel cell-based chemical screen to identify novel inhibitors of intraphagosomal lipolysis in macrophages. Cytometry part A 77: 751-760.
- Smirnova NA, Rakhman I, Moroz N, Basso M, Payappilly J, Kazakov S, Hernandez-Guzman F, Gaisina IN, Kozikowski AP, Ratan RR, Gazaryan IG. (2010) Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation. Chem Biol.Apr 23;17(4):380-91. PMID: 20416509.
- Rosenbaum, A.I., Rujoi, M., Huang, A.Y., Du, H., Grabowski, G.A., and Maxfield, F.R. (2009) Chemical screen to reduce sterol accumulation in Niemann-Pick C disease cells identifies novel lysosomal acid lipase inhibitors. BBA - Molecular and Cell Biology of Lipids 1791:1155-1165.
- Lin, G.; Li, D.; Sorio de Carvalho, L. P.; Deng, H.; Tao, H.; Vogt, G.; Wu, K.; Schneider, J.; Chidawanyika, T.; Warren, J. D.; Li, H.; Nathan, C. (2009) Inhibitors Selective for Mycobacterial versus Human Proteasomes" Nature, DOI: 10.1038/nature08357
- Rodina A, Kang Y, Maharaj R, Gozman A, Taldone T, Caldas-Lopes EM, Clement CC, Brodsky J, Ma Y, Gross SS, Cerchietti L, Melnick A, Freeman BC, Cox MB, Young JC, Chen E, Chirico W, Chiosis G. (2009) Probing malignancy through a novel small molecule heat shock protein 70 modulator. In review Nature chemical biology
- Porotto M, Orefice G, Yokoyama CC, Mungall BA, Realubit R, Sganga ML, Aljofan M, Whitt M, Glickman F, Moscona A. (2009) Simulating henipavirus multicycle replication in a screening assay leads to identification of a promising candidate for therapy J Virol.;83(10):5148-55
- Glickman, J. F. (2009) Assay Development for Protein Kinases and Phosphatases. In A Practical guide to Assay Development for High Throughput Screening Taosheng Chen, ed., Taylor and Francis Publishers, London.
- Blue R, Murcia M, Karan C, Jirousková M, Coller BS. Application of high-throughput screening to identify a novel alphaIIb-specific small- molecule inhibitor of alphaIIbbeta3-mediated platelet interaction with fibrinogen. (2008) Blood. Feb 1;111(3):1248-56
- Farrell, J.*, Ramos, L.*, Tresguerres, M., Kamenetsky, M., Levin, L.R., and Buck, J. (2008). Somatic 'Soluble' adenylyl cyclase isoforms are unaffected in Sacytm1Lex/Sacytm1Lex 'Knockout' mice. PLoS ONE 3(9) e3251.
- Ramos, L.*, Zippin, J.H.*, Kamenetsky, M., Buck, J., and Levin, L.R. (2008). Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells. J. Gen. Physiol. 132: 329-338.
- Kang Y, Taldone T, Clement CC, Fewell SW, Aguirre J, Brodsky JL, Chiosis G. (2008) Design of a fluorescence polarization assay platform for the study of human Hsp70. Bioorg Med Chem Lett. Jul 1;18(13):3749-
- Kenneth D. Bromberg, Avi Ma'ayan, Susana R. Neves, Ravi Iyengar* Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth (2008) Science 320, 903
- Peters U, Cherian J, Kim JH, Kwok BH, Kapoor TM. (2006) Probing cell-division phenotype space and Polo-like kinase function using small molecules Nat Chem Biol. Nov;2(11):618-26.
- Pipalia NH, Huang A, Ralph H, Rujoi M, Maxfield FR (2006) Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells. J Lipid Res. Feb;47(2):284-301
- Wu, K.Y., Zippin, J.H., Huron, D.R., Kamenetsky, M., Hengst, U., Buck, J., Levin, L.R., and Jaffrey, S.R. (2006). Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones. Nature Neuroscience. 9: 1257-1264.
- Moulick K, Clement CC, Aguirre J, Kim J, Kang Y, Felts S, Chiosis G. Synthesis of a red-shifted fluorescence polarization probe for Hsp90. Bioorg. (2006) Med. Chem. Lett., (16):4515-4518.
- Hess, K.C.*, Jones, B.H.*, Marquez, B., Chen, Y., Ord, T.S., Kamenetsky, M., Myamoto, C., Zippin, J.H., Kopf, G.S., Suarez, S.S., Levin, L.R.*, Williams, C.J.*, Buck, J.*, and Moss, S.B.* (2005). 'Soluble' Adenylyl Cyclase mediates Multiple Specific Signaling Events in Sperm Required for Fertilization. Dev. Cell 9: 249-259.
- Han, H., Stessin, A.M., Roberts, J., Hess, K.C., Gautam, N., Kamenetsky, M., Lou, O., Hyde, E., Nathan, N., Muller, W.A., Buck, J., Levin, L.R., and Nathan, C. (2005). Role of Calcium-Sensing Soluble Adenylyl Cyclase in TNF Signal Transduction in Human Neutrophils. J. Exp. Med. 202: 353-361.
- Hotha S, Yarrow JC, Yang JG, Garrett S, Renduchintala KV, Mayer TU, Kapoor TM. (2003) HR22C16: a potent small-molecule probe for the dynamics of cell division Angew Chem Int Ed Engl.May 30;42(21):2379-82
