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Selected Publications:

  1. Hirsch, J., E.H. Ahrens, Jr., D.H. Blankenhorn. Measurement of the human intestinal length in vivo and some causes of variation. Gastroenterology 31:274-284, 1956.

  2. Ahrens, E.H., Jr., J. Hirsch, W. Insull, Jr., R. Blomstrand, T.T. Tsaltas and M .L. Peterson. The influence of dietary fats on serum lipid levels in man. J. Am. Oil Chemists Soc. 34:563-570, 1957.

  3. Hirsch, J. and E. H. Ahrens, Jr. The separation of complex lipide mixtures by the use of silicic acid chromatography. J. Biol. Chem. 233:213-234, 1958.

  4. Hirsch J. Preparation and analytical separation of fatty acids by rubber chromatography. Fed. Proc. 18:, March 1959.

  5. Hirsch, J., J.W. Farquhar, E.H. Ahrens, Jr., M.L. Peterson and W. Stoffel. Studies of adipose tissue in man, a microtechnic for sampling and analysis. Am. J. Clin. Nutr. 8:499-511, 1960.

  6. Hirsch, J. Factice chromatography: An automatically monitored liquid-gel system for the separation of non-polar lipids. J. Lipid Res. 4:1-10, 1963.

  7. Hirsch J. A method for the determination of cell size and cell number in rat and human adipose tissue. Fed. Proc. 25, March-April, 1966.

  8. Hirsch J. Cell lipid content and cell number in obese and non-obese human adipose tissue. Am J Clin. Invest. May 2, 1966.

  9. Hirsch, J. and E. Gallian. Methods for the determination of adipose cell size in man and animals. J. Lipid Res. 9:110-119, 1968.

  10. Salans, L.B., J.L. Knittle and J. Hirsch. The role of adipose cell size and adipose tissue insulin sensitivity in the carbohydrate intolerance of human obesity. J. Clin. Invest. 47:153-165, 1968.

  11. Hirsch, J. and P.W. Han. Cellularity of rat adipose tissue: Effects of growth, starvation, and obesity. J. Lipid Res. 10:77-82, 1969.

  12. Hirsch, J. and J.L. Knittle. Cellularity of obese and nonobese human adipose tissue. Fed. Proc. 29:1516-1521, 1970.

  13. Johnson, P.R., L.M. Zucker, J.A.F. Cruce and J. Hirsch. Cellularity of adipose depots in the genetically obese Zucker rat. J. Lipid Res. 12:706-714, 1971.

  14. Johnson, P.R. and J. Hirsch. Cellularity of adipose depots in six strains of genetically obese mice. J. Lipid Res. 13:2-11, 1972.

  15. Stern, J.S., B.R. Batchelor, N. Hollander, C.K. Cohn and J. Hirsch. Adipose cell size and immunoreactive insulin levels in obese and normal weight adults. Lancet 948-951, 1972.

  16. Stern, J.S., P.R. Johnson, M.R.C. Greenwood, L. M. Zucker and J. Hirsch. Insulin resistance and pancreatic insulin release in the genetically obese Zucker rat. Proc. Soc. Exp. Biol. Med. 139:66-69, 1972.

  17. Johnson, P.R., J.S. Stern, M.R.C. Greenwood, L.M. Zucker and J. Hirsch. Effect of early nutrition on adipose cellularity and pancreatic insulin release in the Zucker rat. J. Nutr. 103:738-743, 1973.

  18. Hirsch, J. The adipose-cell cell hypothesis (editorial). N. Engl. J. Med. 295:389-390, 1976.

  19. Faust, I.M., P.R. Johnson and J. Hirsch. Adipose tissue regeneration following lipectomy. Science 197:391-393, 1977.

  20. Faust, I.M., P.R. Johnson and J. Hirsch. Surgical removal of adipose tissue alters feeding behavior and the development of obesity in rats. Science 197:393-396, 1977.

  21. Johnson, P.R., J.S. Stern, M.R.C. Greenwood and J. Hirsch. Adipose tissue hyperplasia and hyper-insulinemia in Zucker obese female rats. Metabolism 27:(Suppl.2), 1941-1954, 1978.

  22. Faust, I.M., P.R. Johnson and J. Hirsch. Adipose tissue regeneration in adult rats. Proc. Soc. Exp. Biol. Med. 161:111-114, 1979.

  23. Leibel, R.L. and J. Hirsch. Diminished energy requirements in reduced-obese patients. Metabolism 33:164-170, 1984.

  24. Leibel, R.L. and J. Hirsch. Site- and sex-related differences in adrenoreceptor status of human adipose tissue. J. Clin. Endocrinol. Metab. 64:1205-1210, 1987.

  25. Hirsch, J., R.L. Leibel, R. Mackintosh and A. Aguirre. Heart rate variability as a measure of autonomic function during weight change in humans. Am. J. Physiol. 261:R1418-1423, 1991.

  26. Hirsch, J., R. Mackintosh and R. Leibel. Nutritionally-induced changes in parasympathetic function. Brain Res. Bull. 27:541-542, 1991.

  27. Aronne, L.J., R. Mackintosh, R.L. Leibel, M. Rosenbaum and J. Hirsch. Autonomic nervous system activity in weight gain and weight loss. Am. J. Physiol. 269:R222-R225, 1995.

  28. Aronne, L.J., R. Mackintosh, M. Rosenbaum, R.L. Leibel and J. Hirsch. Autonomic nervous system activity in obese and never-obese young men. Obesity Research 5:354-359, 1997.

  29. Hirsch, J., L.C. Hudgins, R.L. Leibel and M. Rosenbaum. Diet composition and energy balance in humans. Am. J. Clin. Nutr. 67:551S-555S, 1998.

  30. Hirsch, J., R.M. Mackintosh and L.J. Aronne. The effects of drugs used to treat obesity on the autonomic nervous system. Obesity Research. 8:227-233, 2000.

  31. Mackintosh, R.M. and Hirsch, J. The effects of leptin administration in non-obese human subjects. Obesity Res. 9:462-469, 2001.